Metabolomics Platform

Metabolomics Platform

 
Sciex QTRAP 6500+ mass spectrometer with SelexION+ ion mobility coupled to Shimadzu Nexera II UHPLC
Lab scene showing a researcher operating a SCIEX QTRAP 6500+ mass spectrometer with SelexION+ ion mobility, coupled to a Shimadzu Nexera II UHPLC system. The researcher wears a lab coat and gloves while handling an autosampler tray connected to stacked UHPLC modules. The blue mass spectrometer unit and connected tubing are visible on a laboratory bench, showing an active use of advanced analytical instrumentation for targeted and quantitative analysis.
Sciex QTRAP 6500+ mass spectrometer with SelexION+ ion mobility coupled to Shimadzu Nexera II UHPLC
  • Targeted quantification of a wide range of small molecules.
  • Up to 6 orders of detector dynamic range
  • Polarity switching speeds of 5 msec
  • Mass range 50-2000 m/z
  • Scan speeds of up to 20,000 Da/second
  • SelexION+ Differential Ion Mobility Technology for added selectivity
  • UHPLC with extended pressure range up to 19,000 psi for the smallest particle columns
  • Increased chromatographic reproducibility through use of micro-volume plungers
  • Autosampler has multiple rinsing lines enabling low sample carry over
  • High-speed injection

 

Agilent 1290 Infinity II UPLC
  • Separation, profiling and quantification of a wide range of small molecules: PEG, dyes, vitamins, organic acids, carbohydrates, triglycerides, phospholipids, FAME, and more….
  • Peptide and protein fractionation for proteomics applications.
  • Flow rate range: 0.05 to 5 mL/min
  • Pressure 1300 bar (18,800 psi)
  • Multicolumn thermostat and multisampler
  • DAD, ELSD and Fluorescence detector allowing detection of a wide range of compounds (absorbing, fluorescent, non-volatile, and semi-volatile compounds)
Laboratory scene showing a researcher seated at a bench operating an Agilent 1290 Infinity II UPLC system. The image shows multiple stacked UPLC modules with solvent bottles on top and tubing connected throughout the system. The researcher wears a lab coat and gloves while working at a computer monitor controlling the instrument. Gas cylinders, drawers, and lab supplies are visible, showing an active use of high‑performance liquid chromatography for analytical research.
Agilent 1290 Infinity II UPLC

 

Agilent GC-MS 5977A
Laboratory bench setup featuring an Agilent GC‑MS 5977A system. The image shows multiple stacked gas chromatography and mass spectrometry modules connected by tubing and cables, with autosampler components mounted above the units. Bottles, control panels, and accessory equipment are visible along the bench, indicating an active analytical laboratory environment used for chemical analysis and compound identification.
Agilent GC-MS 5977A
  • Targeted and untargeted profiling and quantification of volatile compounds for food regulation, environmental analysis, forensic analysis, drug detection, research.
  • Headspace sampler for analysis of volatile and semi-volatile compounds in solid, liquid and gas samples (without sample extraction)
  • NIST and Fiehn GC-MS compound libraries for identification/confirmation of unknown volatile compounds
  • Integrates with Mass Profiler Professional for qualitative and quantitative studies
 
Thermo Q-Exactive – High Field (QE-HF) coupled to Thermo Vanquish H binary UPLC
Laboratory bench setup featuring a Thermo Scientific Q‑Exactive mass spectrometer connected to liquid chromatography components. The image shows stacked analytical modules with solvent bottles on top and a mass spectrometer unit to the right. In the foreground, gloved hands hold a sample tray being loaded into the instrument. Cabinets, tubing, and a computer monitor are visible, showing an active high‑resolution mass spectrometry used for proteomics or metabolomics analysis.
Thermo Q-Exactive
  • Untargeted profiling and quantification of metabolitc compounds
  • High Resolution/Accurate Mass (HR/AM) instrument
  • Resolving power up to 240,000 at 200 m/z
  • Sub ppm mass accuracy
  • Scan speed of 18 Hz at 15,000 resolution
  • Flow rate of the nanopump: 20 nL/min to 1.5 µL/min
  • Pressure to 800 bar (11,600 psi)

PROTEOMICS AND METABOLOMICS