Core Research Facilities

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OUR CORE FACILITIES

When the Center for Biotechnology was formed in 1988, one of the priorities was to develop state-of-the-art core research facilities that would provide the technical expertise and equipment needs of faculty, staff, students and Nebraska-based businesses on a service basis to conduct research in the field of biotechnology. These facilities continue to function to provide access on the University campus to state-of-the-art scientific expertise and equipment that are too costly for individual scientists or businesses to have in the laboratories they direct. Another primary function of the facilities is to provide opportunities for educating students about the modern techniques used in the field of biotechnology.

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MICROSCOPY

Located on the first floor of the George W. Beadle building, the Microscopy Core Research Facility has state of the art imaging systems including light/fluorescence microscopes, confocal laser scanning microscopes and electron microscopes.

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Circular photograph of a laboratory imaging setup showing two people working at microscopes. In the foreground, a computer monitor displays a blue‑tinted microscopic image of cellular structures. In the background, another person looks through the eyepieces of a microscope mounted on an imaging system. The scene shows hands‑on microscopy and image analysis in a research laboratory environment.
Circular abstract graphic with vertical streaks of blended colors transitioning from blue and green on the left to yellow, orange, and red on the right. The smooth color gradient resembles a spectral or fluorescence pattern, commonly associated with flow cytometry or fluorescence‑based data visualization.

FLOW CYTOMETRY

The Flow Cytometry Core Facility provides flow cytometry services to investigators on and off the University of Nebraska-Lincoln campus on a fee for service basis. The core provides comprehensive data collection, data interpretation and education in flow cytometry.

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BIOINFORMATICS

The Bioinformatics Core Research Facility offers education, analysis, and computational services in the area of bioinformatics and computational biology.

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Circular photograph of a computer monitor displaying a genome browser or bioinformatics data visualization with tracks, read alignments, and charts. A person’s hand holding a pencil points to a specific region on the screen, indicating review or discussion of genomic data. The workstation includes electronic components and desk items beneath the monitor, suggesting active data analysis in a research or bioinformatics setting.
Circular photograph of a Cryo‑EM sample preparation component on a laboratory benchtop. The image shows a round holder containing a central metallic Cryo‑EM grid or specimen mount, surrounded by a translucent liquid layer. A plastic syringe and a pen are placed beside the device, indicating preparation, loading, or handling of Cryo‑electron microscopy samples prior to imaging.

CRYOEM

Cryo-EM is a structural biology technique that has progressed exponentially in the last few years. It has an unparalleled capacity to provide near atomic-resolution structures of biological macromolecules. It is also uniquely suited to provide information about molecular rearrangements and interactions that are often essential to the function and mechanism of macromolecular complexes involved in a variety of cellular processes.

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PROTEOMICS AND METABOLOMICS

Newly equipped facility with the latest state-of-the-art mass spectrometers and bioinformatics tools. Suitable for addressing complex proteomics and metabolomics questions at multiple levels.

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Circular photo showing a laboratory environment with large analytical instruments and an enclosed blue anaerobic or glovebox chamber with a round viewing window and caution symbol. Two lab personnel wear lab coats and gloves while working at separate stations with tubing, control panels, and bench equipment. The image highlights hands‑on operation of advanced biotechnology instrumentation in a research lab setting.
Close‑up photograph of gloved hands holding a 10x Genomics microfluidic chip and loading strip. The chip contains multiple small wells and is labeled “10x Genomics.” The hands are positioned over a lab bench, showing preparation or loading of samples for single‑cell genomic analysis.

SINGLE CELL GENOMICS

The Single Cell Genomics Research Facility

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